UVRAG IHC Antibody

Rabbit anti-UVRAG IHC Antibody, Affinity Purified
IHC-00590
$360.00 Request Bulk Quote
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Secondary Antibodies
UVRAG IHC AntibodyUVRAG IHC Antibody
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  • UVRAG IHC Antibody
  • UVRAG IHC Antibody
Quantity:
0.1 ml (50 - 250 slides)
Reactivity:
Human, Mouse
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
p63, DHTX, VPS38, UV radiation resistance-associated gene protein, UV radiation resistance associated, disrupted in heterotaxy, beclin 1 binding protein
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.


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