NEW!
Rabbit anti-Lasu1/Ureb1 IHC Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
Lasu1/Ureb1
Reactivity:
Human
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 2250 and 2300
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Mouse
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Lasu1/Ureb1 is an E3 ubiquitin protein ligase that mediates the ubiquitination of core histones, Mcl-1, Cdc6, and p53. Lasu1/Ureb1 expression is regulated during spermatogenesis and appears to play a role in chromatin modification in germ cells as well as other tissues.
E3 ubiquitin-protein ligase HUWE1
Alternate Names
ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; HECT domain protein LASU1; HECT, UBA and WWE domain-containing protein 1; HECTH9; HECT-type E3 ubiquitin transferase HUWE1; homologous to E6AP carboxyl terminus homologous protein 9; HSPC272; Ib772; large structure of UREB1; LASU1; Mcl-1 ubiquitin ligase E3; MULE; upstream regulatory element-binding protein 1; UREB1; URE-B1; URE-binding protein 1
Applications
