Rabbit anti-RAP1 IHC Antibody
Catalog #
RAP1
Human
IHC
Rabbit
Polyclonal
Whole IgG
Full length
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Repressor/activator protein 1 homolog (RAP1) acts both as a regulator of telomere function and as a transcriptional regulator. RAP1 is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, RAP1 is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NYB0].
Telomeric repeat-binding factor 2-interacting protein 1
Alternate Names
dopamine receptor-interacting protein 5; DRIP5; hRap1; RAP1; RAP1 homolog; repressor/activator protein 1 homolog; telomeric repeat-binding factor 2-interacting protein 1; TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; TRF2-interacting telomeric RAP1 protein
Applications
