Phospho EZH2 (S21) IHC Antibody

Rabbit anti-Phospho EZH2 (S21) IHC Antibody, Affinity Purified
IHC-00388
$385.00 Request Bulk Quote
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Secondary Antibodies
Phospho EZH2 (S21) IHC AntibodyPhospho EZH2 (S21) IHC Antibody
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  • Phospho EZH2 (S21) IHC Antibody
  • Phospho EZH2 (S21) IHC Antibody
Quantity:
0.1 ml (50 - 250 slides)
Reactivity:
Human, Mouse
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
ENX-1, EZH2, KMT6, WVS, ENX1, EZH1, WVS2, EZH2b, KMT6A, Histone-lysine N-methyltransferase EZH2, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, enhancer of zeste homolog 2Drosophila), histone-lysine N-methyltransferase EZH2, lysi
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
EZH2 is a polycomb group enzyme that functions to methylate histone H3-lysine 27 and mediate gene silencing of Homeobox (Hox) genes during development. EZH2 possesses a SET domain which is important to methyltransferase activity. Amplification of EZH2 has been reported in a number of malignancies and may contribute to oncogenesis.
  • Hyland PL et al., Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. J Virol. 2011 Nov;85(21):10999-1006. WB, IHC-P
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