Rabbit anti-JARID1B IHC Antibody
Catalog #
JARID1B
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 1494 and 1544
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Monkey,
Dog
Human
2 - 8 °C
1 year from date of receipt
JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer.
Alternate Names
cancer/testis antigen 31; CT31; histone demethylase JARID1B; JARID1B; jumonji, AT rich interactive domain 1B; jumonji/ARID domain-containing protein 1B; lysine (K)-specific demethylase 5B; lysine-specific demethylase 5B; MRT65; PLU1; PLU-1; PPP1R98; protein phosphatase 1, regulatory subunit 98; PUT1; putative DNA/chromatin binding motif; RBBP2H1A; RBP2-H1; retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A
Applications
