Rabbit anti-GTF2IRD/TFII-IRD1 IHC Antibody
Catalog #
GTF2IRD/TFII-IRD1
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 650 and 700
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Horse,
Dog,
Bovine,
Pig
Human
2 - 8 °C
1 year from date of receipt
GTF2IRD1/TFII-IRD1 possesses five helix-loop-helix GTF2I-like repeats and has been shown to bind the GUCE (GTF2IRD1 upstream response element) regulatory motif found in HOXC8, GOOSECOID, and TROPONININ (SLOW) genes. GTF2IRD1/TFII-IRD1 may be involved in skeletal muscle differentiation and myogenesis. Haploinsufficiency of GTF2IRD1/TFII-IRD1 results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.
General transcription factor II-I repeat domain-containing protein 1
Alternate Names
BEN; binding factor for early enhancer; CREAM1; general transcription factor 3; general transcription factor III; general transcription factor II-I repeat domain-containing protein 1; GTF2I repeat domain-containing protein 1; GTF3; hMusTRD1alpha1; Muscle TFII-I repeat domain-containing protein 1; muscle TFII-I repeat domain-containing protein 1 alpha 1; MUSTRD1; MusTRD1/BEN; RBAP2; slow-muscle-fiber enhancer-binding protein; USE B1-binding protein; WBS; WBSCR11; WBSCR12; Williams-Beuren syndrome chromosomal region 11 protein; williams-Beuren syndrome chromosomal region 12 protein; Williams-Beuren syndrome chromosome region 11
Applications