NEW!
Rabbit anti-Pericentrin/Kendrin IHC Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
Pericentrin/Kendrin
Reactivity:
Human
Applications:
ICC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 175 and 225
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
100 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
Pericentrin (PCNT) is a large centrosomal protein that binds calmodulin and mediates assembly of the mitotic spindle apparatus. Depletion of PCNT has been shown to cause apoptosis and activation of the G2/M checkpoint. Recently, mutations in the pericentrin gene have been identified as the cause of primordial dwarfism type II (MOPDII) and Seckel syndrome. Additionally, in cells of Seckel syndrome patients, PCNT has been found to be important to the DNA damage response and ATR-dependent checkpoint signaling.
Alternate Names
KEN; kendrin; MOPD2; PCN; PCNT2; PCNTB; PCTN2; pericentrin; pericentrin-2; pericentrin-380; pericentrin-B; SCKL4
Applications
