Rabbit anti-NBS1 IHC Antibody
Catalog #
NBS1
Human
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 704 and 754
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Monkey
Human
2 - 8 °C
1 year from date of receipt
Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.
Alternate Names
ATV; AT-V1; AT-V2; cell cycle regulatory protein p95; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; P95; p95 protein of the MRE11/RAD50 complex
Applications