Rabbit anti-CHD3 IHC Antibody
Catalog #
CHD3
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 1950 and 2000
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Monkey,
Dog,
Pig,
Rabbit,
Rat
Human
2 - 8 °C
1 year from date of receipt
CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.
Chromodomain-helicase-DNA-binding protein 3
Alternate Names
ATP-dependent helicase CHD3; CHD-3; chromodomain-helicase-DNA-binding protein 3; hZFH; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-ALPHA; ZFH; zinc finger helicase; zinc-finger helicase (Snf2-like)
Applications
