Rabbit anti-DDX46 IHC Antibody
Catalog #
DDX46
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 981 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Zebra_finch,
Turkey,
Monkey,
Dog,
Chicken,
Pig,
Rabbit,
X_tropicalis,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
DDX46 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX46 is a component of the 17S U2 snRNP complex and plays and important role in pre-mRNA splicing.
Alternate Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; probable ATP-dependent RNA helicase DDX46; Prp5; PRP5 homolog; Prp5-like DEAD-box protein; PRPF5; RNA helicase
Applications