Rabbit anti-ACINUS/ACN1 IHC Antibody
Catalog #
ACINUS/ACN1
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 1291 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Guinea_pig,
Mouse,
Horse,
Monkey,
Dog,
Pig,
Rabbit,
X_laevis,
X_tropicalis,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
Acinus (Apoptotic Chromatin Condensation Inducer of the Nucleus) has been demonstrated to play a dual role in apoptosis and mRNA splicing. A proteolytic fragment of acinus generated by caspase cleavage appears to mediate chromatin condensation and DNA fragmentation. Acinus is also part of the ASAP (apoptosis and splicing-associated protein) complex that is deposited at exon-exon junctions during RNA splicing. In this complex acinus may be involved in pre-mRNA splicing.
Apoptotic chromatin condensation inducer in the nucleus
Alternate Names
ACINUS; ACN; apoptotic chromatin condensation inducer in the nucleus; fSAP152; functional spliceosome-associated protein 152
Applications