Rabbit anti-SUPT5H IHC Antibody
Catalog #
SUPT5H
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 1040 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Turkey,
Monkey,
Dog,
Chicken,
Pig,
Rabbit,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT5H is a subunit of the DRB sensitivity inducing factor (DSIF) along with SUPT4H that functions as a negative elongation factor. DSIF associates with RNA Pol II and may inhibit elongation by pausing and terminating RNA Pol II activity.
Transcription elongation factor SPT5
Alternate Names
DRB sensitivity-inducing factor 160 kDa subunit; DRB sensitivity-inducing factor large subunit; DSIF large subunit; DSIF p160; hSPT5; SPT5; SPT5H; suppressor of Ty 5 homolog; Tat-cotransactivator 1 protein; Tat-CT1; Tat-CT1 protein; transcription elongation factor SPT5
Applications
