Rabbit anti-JMJD1B IHC Antibody
Catalog #
JMJD1B
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 1710 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Guinea_pig,
Mouse,
Horse,
Zebra_finch,
Turkey,
Dog,
Chicken,
Pig,
Rabbit,
Bovine,
Monkey
Human
2 - 8 °C
1 year from date of receipt
JMJD1B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1B was identified as the 5qNCA gene that lies within a locus on chromosome 5 that is frequently deleted in myeloid leukemias and myelodysplasias. JMJD1B has been demonstrated to have growth suppressive activity and is implicated as a tumor suppressor gene.
Alternate Names
5qNCA; C5orf7; jmjC domain-containing histone demethylation protein 2B; JMJD1B; jumonji domain containing 1B; jumonji domain-containing protein 1B; lysine (K)-specific demethylase 3B; lysine-specific demethylase 3B; NET22; nuclear protein 5qNCA
Applications
