Rabbit anti-MED12 IHC Antibody
Catalog #
MED12
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 2150 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Monkey,
Dog,
Pig,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
MED12 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. In this context, MED12 interaction with beta-catenin has been shown to be required for Wnt-signaling dependent transcription.
Mediator of RNA polymerase II transcription subunit 12
Alternate Names
activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; CAGH45; FGS1; HOPA; human opposite paired; MED12S; Mediator complex subunit 12; mediator of RNA polymerase II transcription subunit 12; mediator of RNA polymerase II transcription, subunit 12 homolog; OHDOX; OKS; OPA1; OPA-containing protein; putative mediator subunit 12; thyroid hormone receptor-associated protein complex 230 kDa component; thyroid hormone receptor-associated protein, 230 kDa subunit; TNRC11; TRAP230; trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit); trinucleotide repeat-containing gene 11 protein
Applications