Rabbit anti-PPM1G IHC Antibody
Catalog #
PPM1G
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 400 and 450
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Zebra_finch,
Turkey,
Monkey,
Dog,
Chicken,
Pig,
Rabbit,
X_laevis,
X_tropicalis,
Bovine
Human
2 - 8 °C
1 year from date of receipt
Members of the protein phosphatase 2C (PP2C) family of isoenzymes are serine/threonine protein phosphatases that act as monomers, are magnesium or manganese dependent, and are structurally distinct from PP1, PP2A, and PP2B protein phosphatases. There are 14 mammalian PP2C genes that encode for members of the PP2C family of isoenzymes. Members of this family include PP2C alpha (PPM1A), PP2C beta (PPM1B), PP2C gamma (PPM1G), and PP2C delta (PPM1D). Because PPM1G has been shown to bind and dephosphorylate histones H2A and H2B, it appears to play a role in chromatin remodeling in response to DNA damage.
Alternate Names
PP2CG; PP2CGAMMA; PP2C-gamma; PPP2CG; protein phosphatase 1C; protein phosphatase 1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; protein phosphatase 2C isoform gamma; protein phosphatase magnesium-dependent 1 gamma
Applications
