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Primary Antibodies  

Rabbit anti-PRMT5 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PRMT5

Reactivity:

Human

,

Mouse

Applications:

IHC

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 580 and C-term

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human,

Mouse

Presumed Reactivity

Guinea_pig,

Horse,

Monkey,

Dog,

Pig,

Rabbit,

X_laevis,

X_tropicalis,

Bovine

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT5 interacts with the SWI/SNF complexes and methylates histones H3 and H4. This finding suggests that PRMT5 is involved in the structural modification of chromatin and the regulation of gene transcription.

10419

PRMT5

protein arginine methyltransferase 5

O14744

Protein arginine N-methyltransferase 5

Alternate Names

72 kDa ICln-binding protein; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; IBP72; jak-binding protein 1; JBP1; protein arginine N-methyltransferase 5; shk1 kinase-binding protein 1 homolog; SKB1; SKB1 homolog; SKB1Hs

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.