Rabbit anti-SMAR1/BANP IHC Antibody
Catalog #
SMAR1/BANP
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 425 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Monkey,
Dog,
Rabbit,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.
Alternate Names
BEN domain-containing protein 1; BEND1; Btg3-associated nuclear protein; protein BANP; scaffold/matrix-associated region-1-binding protein; SMAR1; SMARBP1
Applications
