Rabbit anti-Rad6 IHC Antibody
Catalog #
Rad6
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
N-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Zebra_finch,
Monkey,
Bovine,
Chicken,
D_melanogaster,
Pig,
Rabbit,
X_laevis,
X_tropicalis,
Zebrafish,
Rat
Human
2 - 8 °C
1 year from date of receipt
Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.
Alternate Names
E2 ubiquitin-conjugating enzyme A; HHR6A; HR6A; MRXS30; MRXSN; RAD6 homolog A; RAD6A; UBC2; ubiquitin carrier protein A; ubiquitin-conjugating enzyme E2 A; ubiquitin-conjugating enzyme E2A; ubiquitin-protein ligase A
Applications