ASPM IHC Antibody

Rabbit anti-ASPM IHC Antibody, Affinity Purified
IHC-00058
$360.00 Request Bulk Quote
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Secondary Antibodies
ASPM IHC AntibodyASPM IHC Antibody
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  • ASPM IHC Antibody
  • ASPM IHC Antibody
Quantity:
0.1 ml (50 - 250 slides)
Reactivity:
Human
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
Asp homolog, MCPH5, Calmbp1, Abnormal spindle-like microcephaly-associated protein, Abnormal spindle protein homolog, aspabnormal spindle) homolog, microcephaly associatedDrosophila), abnormal spindle-like microcephaly-associated protein
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
ASPM (abnormal spindle-like microcephaly associated) is also known as MCPH5 (autosomal recessive primary microcephaly 5). Defects in ASPM are the cause of microcephaly primary type 5 or microcephaly vera, an autosomal recessive disease characterized by reduced head circumference, small cerebral cortex, and reduced brain weight. At the cellular level, MCPH5 is important to mitotic spindle function and may play a preferential role in prenatal neurogenesis.
  • Griffith E et al., Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nat Genet. 2008 Feb;40(2):232-6.
  • Xu XL et al., The microtubule-associated protein ASPM regulates spindle assembly and meiotic progression in mouse oocytes. PLoS One. 2012;7(11):e49303. IHC-P
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