NEW!
Rabbit anti-REA IHC Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
REA
Reactivity:
Human
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Guinea_pig,
Mouse,
Monkey,
Rabbit
Antigen Species
Human
Concentration
100 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.
Alternate Names
BAP; Bap37; BCAP37; B-cell associated protein; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; p22; PNAS-141; prohibitin-2; REA; repressor of estrogen receptor activitY
Applications
