NEW!
Goat anti-MCM4 IHC Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
MCM4
Reactivity:
Human
Applications:
IHC
Host:
Goat
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 325 and 375
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Guinea_pig,
Monkey,
Rabbit
Antigen Species
Human
Concentration
500 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM4 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity. MCM4 is phosphorylated by CDC2 kinase resulting in a reduction of helicase activity and chromatin binding.
DNA replication licensing factor MCM4
Alternate Names
CDC21; CDC21 homolog; CDC54; DNA replication licensing factor MCM4; hCdc21; homolog of S. pombe cell devision cycle 21; IMD54; minichromosome maintenance deficient 4; NKCD; NKGCD; P1-CDC21
Applications
