Rabbit anti-PELP1/MNAR IHC Antibody
Catalog #
PELP1/MNAR
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 1000 and 1050
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the “signalsome” involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.
Proline-, glutamic acid- and leucine-rich protein 1
Alternate Names
MNAR; modulator of non-genomic activity of estrogen receptor; P160; proline and glutamic acid rich nuclear protein; proline-, glutamic acid- and leucine-rich protein 1; transcription factor HMX3
Applications
