SKP2 Antibody AbVantage™ Pack

SKP2 Antibody AbVantage™ Pack
A310-883A
$437.00 Request Bulk Quote
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Secondary Antibodies
Quantity:
1 each of A302-436A and A302-437A
Reactivity:
Human
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
p45FBXL1, FBL1, FLB1, p45S-phase kinase-associated protein 2, Cyclin-A/CDK2-associated protein p45, F-box protein F-box/LRR-repeat protein 1, S-phase kinase-associated protein 2, E3 ubiquitin protein ligase, CDK2/cyclin A-associated protein p45
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
S-phase kinase-associated protein 2 (SKP2) is a member of the F-box family of proteins. It is the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. SKP2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13309]


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