Mediator complex subunit 15 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. MED15 is required for cholesterol-dependent gene regulation. It also positively regulates the Nodal signaling pathway. Alternative names for MED15 include positive cofactor 2 glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, TPA-inducible gene 1 protein, TIG-1, activator-recruited cofactor 105 kDa component, ARC105, CTG repeat protein 7a, trinucleotide repeat-containing gene 7 protein, CAG7A, TIG1, CTG7A, PCQAP, and TNRC7. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96RN5]
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| Mail: |
Bethyl Laboratories |
| |
P.O. Box 850 |
| |
Montgomery, TX 77356 USA |
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Some product information in the catalog may be abbreviated. Before ordering, we recommend that you review specifications of the product as published in the product insert available at our website or call and request a copy from your distributor. Product inserts on the website reflect, in general, the applications and conditions for use. Products should be used in accordance with the insert shipped with the product. Bethyl Laboratories reserves the right to change product specifications without prior notification. All products supplied by Bethyl Laboratories are warranted to meet our published specifications when used under normal conditions in your laboratory.
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Miscellaneous
If any provision of these Terms & Conditions is held to be invalid or unenforceable, such provision shall be struck and the remaining provisions shall be enforced. Headings are for reference purposes only and in no way define, limit, construe or describe the scope or extent in such section. You may not sell, assign, or otherwise transfer your account. Bethyl Laboratories may assign or transfer its rights with regard to your account and these Terms & Conditions. Bethyl Laboratories' failure to act with respect to any failure by you or others to comply with these Terms & Conditions does not waive Bethyl Laboratories' right to act with respect to subsequent or similar failures. These Terms & Conditions set forth the entire understanding and agreement between you and Bethyl Laboratories with respect to the subject matter hereof. This paragraph survives expiration or termination of these Terms & Conditions.
