NFRKB Antibody AbVantage™ Pack

NFRKB Antibody AbVantage™ Pack
A310-508A
$437.00 Request Bulk Quote
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Secondary Antibodies
Quantity:
1 each of A301-459A and A301-460A
Reactivity:
Human
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
INO80G, Nuclear factor related to kappa-B-binding protein, DNA-binding protein R kappa-B, INO80 complex subunit G, nuclear factor related to kappaB binding protein, nuclear factor related to kappa-B-binding protein, DNA-binding protein R kappa B
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.


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