ACC1/ACC-alpha Antibody AbVantage™ Pack

ACC1/ACC-alpha Antibody AbVantage™ Pack
A310-320A
$437.00 Request Bulk Quote
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Secondary Antibodies
Quantity:
1 each of A300-986A and A300-987A
Reactivity:
Human
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
ACC-alpha, ACACA, ACC1, ACCA, ACAACC-alpha, Acetyl-CoA carboxylase 1, acetyl-CoA carboxylase alpha, acetyl-CoA carboxylase 1, acetyl-Coenzyme A carboxylase alpha
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
ACC1/ACC-alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA in the enzymatic pathway of long-chain fatty-acid synthesis. ACC1/ACC-alpha has been identified as a partner of BRCA1. Through this interaction, ACC1/ACC-alpha may contribute to the tumor suppressor activity of BRCA1 as demonstrated by the finding that disruption of this interaction increases lipid synthesis in mammary epithelial cells. In this context, lipogenesis has been closely linked to tumorigenesis and ACC1/ACC-alpha has been found to be highly expressed in human breast carcinomas.


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