Cul4a Antibody AbVantage™ Pack

Cul4a Antibody AbVantage™ Pack

Gene and Protein Information


  • Liu J et al. CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis. Nat Commun. 2014;5:3924. WB
  • Ong SS et al. Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2. Biochem J. 2014;459(1):193-203. WB
  • Zhang S et al. A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. J Biol Chem. 2013;288(41):29550-61. WB
  • Huh J et al. CRL4CDT2 targets CHK1 for PCNA-independent destruction. Mol Cell Biol. 2012 Oct 29.
  • Gao Y et al. PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis. Mol Cell Biol. 2012 Oct 15.
  • Liu L et al. Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Res. 2012 Aug;22(8):1258-69. WB
  • Li Y et al. The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase. J Biol Chem. 2011 Dec 2;286(48):41344-52. WB, ICC
  • Vaites LP et al. The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation. Mol Cell Biol. 2011 Nov;31(22):4513-23. WB
  • Jiang L et al. Cullin-4A·DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis. J Biol Chem. 2011 Mar 4;286(9):6971-8. WB
  • Ishii T et al. Proliferating cell nuclear antigen-dependent rapid recruitment of Cdt1 and CRL4Cdt2 at DNA-damaged sites after UV irradiation in HeLa cells. J Biol Chem. 2010 Dec 31;285(53):41993-2000. ICC
  • Maddika S et al. Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase. Nat Cell Biol. 2009 Apr;11(4):409-19. WB
  • Aggarwal P et al. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev. 2007 Nov 15;21(22):2908-22. WB
  • More...
Ordering Information
Catalog #SizePrice
A310-224A1 Pack $472Add to Cart
Includes: 1 each of A300-738A and A300-739A
Bulk Quote
100% Guaranteed
Bethyl guarantees that its products will work under the same conditions stated on the product datasheet. We offer comprehensive technical support should one of our products fail to return satisfactory results when used in the species, application and under the same conditions stated on the datasheet. Bethyl will offer a full product replacement, credit or refund if technical support is unable to optimize conditions. Full details…

Datasheets and Documents

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