Rabbit anti-CCDC94 Antibody
Catalog #
CCDC94
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 273 and 323
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
CCDC94 is part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. CCDC94 also plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. CCDC94 may protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BW85].
Alternate Names
CCDC94; coiled-coil domain containing 94; coiled-coil domain-containing protein 94; YJU2 splicing factor homolog
Applications