NEW!
Rabbit anti-ITGA2/CD49B Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
ITGA2/CD49B
Reactivity:
Human
Applications:
WB
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 25 and 75
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)
10 µl (1000 µg/ml)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
Integrin alpha-2 is product of the gene ITGA2 (aka CD49B). Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. This receptor mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia [taken from NCBI Entrez Gene (Gene ID: 3673) and UniProtKB (Entry: P17301)].
Alternate Names
alpha 2 subunit of VLA-2 receptor; BR; CD antigen CD49b; CD49 antigen-like family member B; CD49B; collagen receptor; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha-2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA-2 subunit alpha; VLAA2
Applications
