SENP1 Antibody

Rabbit anti-SENP1 Antibody, Affinity Purified
A302-928A
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Secondary Antibodies
SENP1 Antibody
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Quantity:
0.1 ml
Reactivity:
Human
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
SuPr-2, Sentrin-specific protease 1, Sentrin/SUMO-specific protease SUMO1/sentrin specific peptidase 1, sentrin-specific protease 1, SUMO1/sentrin specific protease 1, sentrin/SUMO-specific protease SENP1
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
SENP1 (sentrin-specific protease) functions as a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugation of SUMO1 from HDAC1 decreases its transcriptional repression activity. SENP1 also deconjugates SUMO1 from HIPK2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9P0U3].
  • Li R et al., Akt SUMOylation regulates cell proliferation and tumorigenesis. Cancer Res. 2013 Jul 24. [Epub ahead of print] WB
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