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Primary Antibodies  

Rabbit anti-Dcp2 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (11)
Target:

Dcp2

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 370 and 420

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 ��g/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

mRNA-decapping enzyme 2 (Dcp2) is required for both normal mRNA turnover and nonsense-mediated mRNA decay. Dcp2 plays a role in replication-dependent histone mRNA degradation. It removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IU60].

167227

DCP2

decapping mRNA 2

Q8IU60

m7GpppN-mRNA hydrolase

Alternate Names

DCP2 decapping enzyme homolog; hDpc; m7GpppN-mRNA hydrolase; mRNA-decapping enzyme 2; Nucleoside diphosphate-linked moiety X motif 20; nudix (nucleoside diphosphate linked moiety X)-type motif 20; Nudix motif 20; NUDT20

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.