AF4 Antibody

Rabbit anti-AF4 Antibody, Affinity Purified
A302-344A
$314.00 Request Bulk Quote
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Secondary Antibodies
AF4 AntibodyAF4 Antibody
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  • AF4 Antibody
  • AF4 Antibody
Quantity:
0.1 ml (20 - 100 blots)
Reactivity:
Human
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
Protein FEL, Protein AF-4, AFF1, MLLT2, PBM1, protein AF-4, AF4/FMR2 family member 1, ALL1-fused gene from chromosome 4 protein, Proto-oncogene AF4/FMR2 family, member 1, proto-oncogene pre-B-cell monocytic leukemia partner 1, myeloid/lymphoi
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
AF4 is a member of the AF4/LAF4/FMR2 (ALF) family of transcription cofactors. It has been identified as part of a translocation [t(4:11)(q21;q23)] found in patients with acute leukemia involving MLL/HRX. AF4 functions as a cofactor of transcriptional elongation and chromatin remodeling.
  • Esposito G et al., Protein network study of human AF4 reveals its central role in RNA Pol II-mediated transcription and in phosphorylation-dependent regulatory mechanisms. Biochem J. 2011 Aug 15;438(1):121-31. WB
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