Rabbit anti-TRIM25 Antibody
Catalog #
TRIM25
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 75 and 125
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
TRIM (tripartite motif) proteins, also known as RBCC (RING, B-box, coiled-coil) proteins, are defined by the presence of a tripartite structural motif composed of a RING domain, one or two B-box motifs, and a coiled-coil region. TRIM proteins have been found to be involved in a variety of cellular processes such as apoptosis, proliferation, differentiation, and innate immunity. Of these processes, the most intriguing is their involvement in the innate immune response. TRIM25 has been demonstrated to mediate ubiquitination of the cytosolic receptor retinoic acid-inducible gene-I (RIG-I) in response to viral infection.
Alternate Names
E3 ubiquitin/ISG15 ligase TRIM25; EFP; estrogen-responsive finger protein; RING finger protein 147; RING-type E3 ubiquitin transferase; RING-type E3 ubiquitin transferase TRIM25; RNF147; tripartite motif protein TRIM25; tripartite motif-containing protein 25; ubiquitin/ISG15-conjugating enzyme TRIM25; Z147; Zinc finger protein 147; zinc finger protein 147 (estrogen-responsive finger protein); zinc finger protein-147; ZNF147
Applications