/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-PAM Antibody
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Primary Antibodies  

Rabbit anti-PAM Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (2)
Target:

PAM

Reactivity:

Human

Applications:

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 2425 and 2475

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway.

23077

MYCBP2

MYC binding protein 2, E3 ubiquitin protein ligase

O75592

E3 ubiquitin-protein ligase MYCBP2

Alternate Names

E3 ubiquitin-protein ligase MYCBP2; Highwire; myc-binding protein 2; Myc-bp2; PAM; pam/highwire/rpm-1 protein; Phr; protein associated with Myc; RING-type E3 ubiquitin transferase MYCBP2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).