Rabbit anti-IKK-beta Antibody
Catalog #
IKK-beta
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 706 and 756
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
IKK-beta (Inhibitor of nuclear factor kappa B kinase subunit beta) is one of three subunits that comprise the IKK complex. The IKK complex consists of two catalytic subunits, IKK-alpha and IKK-beta, and a regulatory subunit IKK-gamma/NEMO. As a kinase, IKK functions to phosphorylate members of the NF-kappa B inhibitor proteins, the I-kappa B proteins. Phosphorylation of I-kappa B proteins results in the ubiquitination and degradation of I kappa B and the release and translocation of the NF-kappa B transcription factor to the nucleus where it may function to activate a vast number of genes.
Inhibitor of nuclear factor kappa-B kinase subunit beta
Alternate Names
I-kappa-B kinase 2; I-kappa-B-kinase beta; IkBKB; IKK2; IKKB; IKK-B; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta
Applications