Rabbit anti-PRKAR2A/PKA-RIIalpha Antibody
Catalog #
PRKAR2A/PKA-RIIalpha
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 50 and 100
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
PRKAR2A/PKA-RIIalpha (cAMP-dependent protein kinase type II-alpha regulatory subunit) is one of 4 isoforms of regulatory subunits of the cAMP-dependent protein kinase (PKA). RI and RII are the two major classes of regulatory subunits. RI and RII each have an alpha and beta isoform. The regulatory subunits perform non-redundant functions as receptors for CAMP signals and for the differential regulation of PKA activity. The PRKAR2A/PKA-RIIalpha functions as an inhibitor of the PKA holoenzyme. PRKAR2A/PKA-RIIalpha subunits have been found to interact with A-kinase anchoring proteins (AKAPs), proteins that function to target the subcellular localization of PKA.
cAMP-dependent protein kinase type II-alpha regulatory subunit
Alternate Names
cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; PKR2; PRKAR2; protein kinase A, RII-alpha subunit; protein kinase, cAMP-dependent, regulatory subunit type II alpha
Applications