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Rabbit anti-JMJD1A/JHDM2A Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

JMJD1A/JHDM2A

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1271 and 1321

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

JMJD1A/JHDM2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in the regulation of chromatin dynamics and influences transcriptional activation and suppression. JMJD1A/JHDM2A specifically demethylates mono- and dimethyl-histone 3 lysine 9. Demethylation of histones by JMJD1A has been shown to facilitate transcriptional activation by the androgen receptor and promote transcription of smooth muscle cell differentiation marker.

55818

KDM3A

lysine demethylase 3A

Q9Y4C1

Lysine-specific demethylase 3A

Alternate Names

JHDM2A; JHMD2A; jmjC domain-containing histone demethylation protein 2A; JMJD1; JMJD1A; jumonji C domain-containing histone demethylase 2A; jumonji domain-containing protein 1A; lysine (K)-specific demethylase 3A; lysine-specific demethylase 3A; testis-specific protein A; TSGA

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.