NEW!
Rabbit anti-Rad18 Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
Rad18
Reactivity:
Human
Applications:
IP
,WB
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 445 and 495
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)
10 µl (200 µg/ml)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
Rad18 is an E3 ubiquitin-protein ligase that associates with the E2 ubiquitin conjugating enzyme UBE2B (Rad6b) and monoubiquitinates PCNA on stalled replication forks. This activity promotes the recruitment of DNA repair polymerases such as DNA polymerase eta (Poleta) and translesion synthesis at DNA lesions.
Alternate Names
E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; postreplication repair protein RAD18; RAD18 homolog; RAD18, S. cerevisiae, homolog; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73
Applications