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Rabbit anti-ATRX Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

ATRX

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 2442 and C-term

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

ATRX (alpha-thalassemia mental retardation X-linked) is a chromatin remodeling protein and transacting regulator of globin gene expression that has been linked to several X-linked mental retardation syndromes and hematologic diseases such as myelodysplasia. ATRX possesses an ATPase/helicase domain and is related to the SWI/SNF family of proteins. Mutations in ATRX have been demonstrated to cause changes in DNA methylation patterns and gene expression important to development.

546

ATRX

ATRX, chromatin remodeler

P46100

Transcriptional regulator ATRX

Alternate Names

alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); ATP-dependent helicase ATRX; JMS; MRX52; RAD54; RAD54L; transcriptional regulator ATRX; XH2; X-linked helicase II; X-linked nuclear protein; XNP; ZNF-HX

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.