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Primary Antibodies  

Rabbit anti-JMJD2C Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (19)
Target:

JMJD2C

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 475 and 525

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

JMJD2C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2C, also known as GASC1 (gene amplified in squamous cell carcinoma), has been found to be amplified in several esophageal squamous carcinomas and inhibition of JMJD2C/GASC1 expression results in decreased cellular proliferation.

23081

KDM4C

lysine demethylase 4C

Q9H3R0

Lysine-specific demethylase 4C

Alternate Names

GASC1; GASC-1 protein; gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain-containing histone demethylation protein 3C; JMJD2C; jumonji domain-containing protein 2C; lysine (K)-specific demethylase 4C; lysine-specific demethylase 4C; TDRD14C; tudor domain containing 14C

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.