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Primary Antibodies

Rabbit anti-PP2A Antibody

Name: Rabbit anti-PP2A Antibody
Brand: Bethyl Laboratories®
SKU: A300-731A
Price: 121 USD

Bethyl Laboratories®

Catalog #

Citations (2)

Target:

PP2A

Reactivity:

Human

Mouse

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications

Verified Reactivity

Human,

Mouse

Presumed Reactivity

Rat

Antigen Species

Human

Concentration

200 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

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Additional Product Information

PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. PP2A encodes the beta isoform of the catalytic subunit (PP2CB). Chk2 has been shown to be negatively regulated and dephosphorylated by PP2A. Several proteins have been shown to associate with PP2A and regulate its activity such as eRF1, Hox11, CK2, and Igbp1/alpha4. Rapamycin has been shown to dissociate PP2A from alpha-4 and inhibit proliferation. This result suggests an alternative positive regulatory role of PP2A in cell proliferation.

Gene ID:

5516

Gene Symbol:

PPP2CB

Gene Name:

protein phosphatase 2 catalytic subunit beta

Uniprot ID:

P62714

Protein Name:

Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Alternate Names

PP2Abeta; PP2A-beta; PP2CB; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; testicular tissue protein Li 146

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Rabbit anti-PP2A Antibody

Catalog #

PP2A

Human

Mouse

WB

Rabbit

Polyclonal

Whole IgG

between 1 and 50

IgG

Unconjugated

Antigen Affinity Purified

Human,

Mouse

Rat

Human

2 - 8 °C

1 year from date of receipt

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

5516

PPP2CB

protein phosphatase 2 catalytic subunit beta

P62714

Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).