PTEN Antibody

Rabbit anti-PTEN Antibody, Affinity Purified
A300-701A
$375.00 Request Bulk Quote
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Secondary Antibodies
PTEN AntibodyPTEN AntibodyPTEN Antibody
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  • PTEN Antibody
  • PTEN Antibody
  • PTEN Antibody
Quantity:
0.1 ml (20 - 100 blots)
Reactivity:
Human, Mouse
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
MMAC1, TEP1, BZS, DEC, CWS1, GLM2, MHAM, PTEN1, 10q23del, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, phosphatase and
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling.
  • Wan X et al., Oxidative inactivation of the lipid phosphatase phosphatase and tensin homolog on chromosome ten (PTEN) as a novel mechanism of acquired long QT syndrome. J Biol Chem. 2011 Jan 28;286(4):2843-52. IP
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