Phospho RNA Polymerase II (S5) Antibody

Description

Rabbit anti-Phospho RNA Polymerase II (S5) Antibody, Affinity Purified

Catalog No.A300-655A

Price$335.00 Request Bulk Quote

Data Sheet

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Secondary Antibodies Positive Controls

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Product Information
Background
Related Products
Citations
Ordering Information

Quantity:

0.1 ml (25 - 200 blots)

Reactivity:

Human, Mouse

100% Sequence Identity:

Rat, D. melanogaster, Zebrafish, X. tropicalis, Bovine, Dog more...

Format:

Whole IgG

Applications:

WB, IHC-P, IF

GeneID URL:

5430

ProteinID URL:

NP_000928.1

Alternative Names:

DNA-directed RNA polymerase II subunit RPB1 antibody, DNA directed RNA polymerse II subunit A antibody, DNA-directed RNA polymerase II largest subunit antibody, POLR2A antibody, RPO2 antibody, POLRA antibody, RPBh1 antibody, RPOL2 antibody, RpIILS antibody, hsRPB1 antibody, hRPB220 antibody, MGC75453 antibody

Host:

Rabbit

Antibody Type:

Polyclonal

Purity:

Antigen Affinity Purified

Conjugate:

Unconjugated

Physical State:

Liquid

The RNA polymerase II subunit B1 (RPB1) is the largest subunit of the RNA polymerase II core complex. RNA polymerase II holoenzyme functions to transcribe DNA into messenger RNA in eukaryotes. RPB1 forms the DNA binding domain of the polymerase that forms a cleft that grabs the incoming DNA template to translocate the holoenzyme across the RNA-DNA hybrid.

SubType	Description	Catalog No.
Positive Controls	HeLa Whole Cell Lysate	CL300-100
PRIMARY ANTIBODIES	Rabbit anti-MED12 Antibody, Affinity Purified	A300-774A
PRIMARY ANTIBODIES	Rabbit anti-MED18 Antibody, Affinity Purified	A300-777A
PRIMARY ANTIBODIES	Rabbit anti-Phospho RNA Polymerase II (S2) Antibody, Affinity Purified	A300-654A
PRIMARY ANTIBODIES	Rabbit anti-RNA Polymerase II Antibody, Affinity Purified	A300-653A
PRIMARY ANTIBODIES	RNA Polymerase II Antibody AbVantage™ Pack	A310-190A
PRIMARY ANTIBODIES	Rabbit anti-SUPT6H Antibody, Affinity Purified	A300-801A
PRIMARY ANTIBODIES	Rabbit anti-SUPT6H Antibody, Affinity Purified	A300-803A
PRIMARY ANTIBODIES	Rabbit anti-SUPT6H Antibody, Affinity Purified	A300-802A
PRIMARY ANTIBODIES	Rabbit anti-TCEB3 Antibody, Affinity Purified	A300-943A
PRIMARY ANTIBODIES	Rabbit anti-TCEB3 Antibody, Affinity Purified	A300-942A
PRIMARY ANTIBODIES	Rabbit anti-TCEB3 Antibody, Affinity Purified	A300-944A

Garrido-Lecca A et al., RNA polymerase II C-terminal domain phosphorylation patterns in Caenorhabditis elegans operons, polycistronic gene clusters with only one promoter. Mol Cell Biol. 2010 Aug;30(15):3887-93. ChIP
PubMed: 20498277
Glover-Cutter K et al., TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II. Mol Cell Biol. 2009 Oct;29(20):5455-64. WB
PubMed: 19667075
Larochelle S et al., Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Mol Cell. 2007 Mar 23;25(6):839-50. WB
PubMed: 17386261
Leuenroth SJ et al., Triptolide-induced transcriptional arrest is associated with changes in nuclear substructure. Cancer Res. 2008 Jul 1;68(13):5257-66. WB, ICC
PubMed: 18593926
Lucio-Eterovic AK et al., Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16952-7. WB
PubMed: 20837538
Ma Y et al., CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner. J Biol Chem. 2010 Mar 26;285(13):9813-22. WB
PubMed: 20106982
Nergadze SG et al., CpG-island promoters drive transcription of human telomeres. RNA. 2009 Dec;15(12):2186-94. ChIP
PubMed: 19850908
Nordick K et al., Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II. Eukaryot Cell. 2008 Jul;7(7):1158-67. WB
PubMed: 18469135
Parker JB et al., A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function. Mol Cell Biol. 2012 May;32(9):1654-70. ChIP
PubMed: 22371484
Schwer B et al., Punctuation and syntax of the RNA polymerase II CTD code in fission yeast. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18024-9. WB
PubMed: 23071310
Wu Y et al., Cyclin-dependent kinase 7/9 inhibitor SNS-032 abrogates FIP1-like-1 platelet-derived growth factor receptor α and bcr-abl oncogene addiction in malignant hematologic cells. Clin Cancer Res. 2012 Apr 1;18(7):1966-78. WB
PubMed: 22447844

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