LOK Antibody

Rabbit anti-LOK Antibody, Affinity Purified
A300-399A
$314.00 Request Bulk Quote
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Secondary Antibodies
LOK AntibodyLOK Antibody
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  • LOK Antibody
  • LOK Antibody
Quantity:
0.1 ml (20 - 150 blots)
Reactivity:
Human
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
STK10, PRO2729, Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, serine/threonine kinase 10, serine/threonine-protein kinase 10, lymphocyte-oriented kinase
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
LOK is a member of the Ste20 family of serine-threonine protein kinases. LOK associates with polo-like 1 kinase (PLK1) and may function to regulate its kinase activity. LOK has also been demonstrated to be involved in the regulation of the CD28 response-element in T-cells via the mitogen activated protein kinase kinase 1 pathway.
  • Yamamoto N et al., Off-target serine/threonine kinase 10 inhibition by erlotinib enhances lymphocytic activity leading to severe skin disorders. Mol Pharmacol. 2011 Sep;80(3):466-75. WB
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