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Rabbit anti-FUS Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

FUS

Reactivity:

Human

,

Mouse

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 500 and C-term

Isotype:

IgG

Conjugation:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human,

Mouse

Presumed Reactivity

Bovine

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.

2521

FUS

FUS RNA binding protein

P35637

RNA-binding protein FUS

Alternate Names

75 kDa DNA-pairing protein; ALS6; ETM4; FUS/ERG chimeric protein; FUS/ERG fusion protein; FUS1; fused in sarcoma; fusion gene in myxoid liposarcoma; fus-like protein; heterogeneous nuclear ribonucleoprotein P2; HNRNPP2; oncogene FUS; oncogene TLS; POMP75; RNA-binding protein FUS; TLS; translocated in liposarcoma protein

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.