PCNA Antibody

Rabbit anti-PCNA Antibody, Affinity Purified
A300-277A
$314.00 Request Bulk Quote
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Secondary Antibodies
PCNA AntibodyPCNA AntibodyPCNA AntibodyPCNA Antibody
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  • PCNA Antibody
  • PCNA Antibody
  • PCNA Antibody
  • PCNA Antibody
Quantity:
0.1 ml (50 - 200 blots)
Reactivity:
Human, Mouse
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
Cyclin, cyclin, Proliferating cell nuclear antigen, proliferating cell nuclear antigen, DNA polymerase delta auxiliary protein
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
  • Ramos-Nino ME et al., HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway. Am J Respir Cell Mol Biol. 2008 Feb;38(2):209-17. WB
  • Szczesny B et al., Long patch base excision repair in mammalian mitochondrial genomes. J Biol Chem. 2008 Sep 26;283(39):26349-56. WB
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