DHX15 Antibody

Rabbit anti-DHX15 Antibody, Affinity Purified
A300-119A
$314.00 Request Bulk Quote
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Secondary Antibodies
DHX15 Antibody
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Quantity:
0.1 ml (100 - 300 blots)
Reactivity:
Human
100% Sequence Identity:
Format:
Whole IgG
Applications:
GeneID URL:
ProteinID URL:
Alternative Names:
DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p, DEAD/H box-15, RNA helicase 2, Putative pre-mRNA-splicing factor ATP-dependent RNA helicase ATP-dependent RNA helicase #46, DEAH box protein 15, DEAHAsp-Glu-Ala-His) box helicase 15, putative pre-mRN
Host:
Rabbit
Antibody Type:
Polyclonal
Purity:
Antigen Affinity Purified
Conjugate:
Unconjugated
Physical State:
Liquid
DHX15 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DHX15 is the human ortholog of the yeast Prp43 protein. DHX15 has been demonstrated to function in ribosome biogenesis and pre-mRNA splicing.
  • Fukuda T et al., DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol. 2007 May;9(5):604-11.
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