Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.
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Fax: 1-936-597-6105 (24 hour)
Email: orders@bethyl.com
| Mail: |
Bethyl Laboratories |
| |
P.O. Box 850 |
| |
Montgomery, TX 77356 USA |
When placing orders, please provide the following information:
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If an error by Bethyl Laboratories results in shipment of an incorrect order, Bethyl Laboratories will, at its sole option, either ship a replacement at no charge or credit your account for the purchase price of the original product shipped in error plus shipping charges. If an error by you results in the shipment of an incorrect order and is reported to Bethyl Laboratories within 48 hours, you may obtain a Return Authorization and return products(s) for a replacement or credit.
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Limited Warranty
Some product information in the catalog may be abbreviated. Before ordering, we recommend that you review specifications of the product as published in the product insert available at our website or call and request a copy from your distributor. Product inserts on the website reflect, in general, the applications and conditions for use. Products should be used in accordance with the insert shipped with the product. Bethyl Laboratories reserves the right to change product specifications without prior notification. All products supplied by Bethyl Laboratories are warranted to meet our published specifications when used under normal conditions in your laboratory.
BETHYL LABORATORIES DOES NOT MAKE ANY OTHER WARRANTY OR REPRESENTATION WHATSOEVER, WHETHER EXPRESS OR IMPLIED, WITH RESPECT TO THESE PRODUCTS. IN PARTICULAR, BETHYL LABORATORIES DOES NOT MAKE ANY WARRANTY OF SUITABILITY, NON-INFRINGEMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OF ANY PRODUCT.
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You hereby agree that the only proper jurisdiction and venue for any dispute with Bethyl Laboratories or to products purchased from Bethyl Laboratories, is in the state and federal courts in the State of Texas, U.S.A. You further agree and consent to the exercise of personal jurisdiction in these courts in connection with any dispute involving Bethyl Laboratories or its affiliates, employees, officers, directors, agents and providers. Any claims relating to the information, services or products available in this catalog will be governed by the laws of the State of Minnesota, excluding the application of its conflicts of law rules. You agree that any cause of action arising out of or relating to these Terms & Conditions will be commenced by you within one (1) year after such cause of action arose. Actions not commenced by you within one (1) year are permanently barred. This paragraph survives expiration or termination of these Terms & Conditions.
Miscellaneous
If any provision of these Terms & Conditions is held to be invalid or unenforceable, such provision shall be struck and the remaining provisions shall be enforced. Headings are for reference purposes only and in no way define, limit, construe or describe the scope or extent in such section. You may not sell, assign, or otherwise transfer your account. Bethyl Laboratories may assign or transfer its rights with regard to your account and these Terms & Conditions. Bethyl Laboratories' failure to act with respect to any failure by you or others to comply with these Terms & Conditions does not waive Bethyl Laboratories' right to act with respect to subsequent or similar failures. These Terms & Conditions set forth the entire understanding and agreement between you and Bethyl Laboratories with respect to the subject matter hereof. This paragraph survives expiration or termination of these Terms & Conditions.
