Rabbit anti-BLM Antibody
Catalog #
BLM
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1375 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Human
2 - 8 °C
1 year from date of receipt
Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.
Alternate Names
Bloom syndrome protein; Bloom syndrome RecQ like helicase; Bloom syndrome, RecQ helicase-like; BS; DNA helicase, RecQ-like type 2; MGRISCE1; recQ protein-like 3; RECQ2; RECQL2; RECQL3
Applications