Rabbit anti-SMC4 Antibody
Catalog #
SMC4
Human
ICC-IF
,WB
Rabbit
Polyclonal
Whole IgG
between 600 and 650
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse
Human
2 - 8 °C
1 year from date of receipt
SMC (Structural maintenance of chromosomes) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.
Structural maintenance of chromosomes protein 4
Alternate Names
CAPC; CAP-C; chromosome-associated polypeptide C; hCAP-C; SMC protein 4; SMC-4; SMC4 structural maintenance of chromosomes 4-like 1; SMC4L1; structural maintenance of chromosomes protein 4; XCAP-C homolog
Applications